Connections between mRNA 3' end processing and transcription termination.

by: S Buratowski

Current opinion in cell biology, Vol. 17, No. 3. (June 2005), pp. 257-261.

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Discoveries within the last few years have revealed that the multiple steps in gene expression are remarkably integrated. There have recently been several advances in deciphering how mRNA 3' end processing is linked with transcription elongation and termination. It has been known for quite a long time that transcription termination is somehow intertwined with polyadenylation, but it is still unclear exactly how these two processes influence each other. Some recent reports are shedding light on these connections.

@article{citeulike:2928913, abstract = {Discoveries within the last few years have revealed that the multiple steps in gene expression are remarkably integrated. There have recently been several advances in deciphering how mRNA 3' end processing is linked with transcription elongation and termination. It has been known for quite a long time that transcription termination is somehow intertwined with polyadenylation, but it is still unclear exactly how these two processes influence each other. Some recent reports are shedding light on these connections.}, address = {Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA. SteveB@hms.harvard.edu}, author = {Buratowski, S. }, citeulike-article-id = {2928913}, doi = {10.1016/j.ceb.2005.04.003}, issn = {0955-0674}, journal = {Current opinion in cell biology}, keywords = {polyadenylation, review, termination, transcription}, month = {June}, number = {3}, pages = {257--261}, posted-at = {2008-06-26 09:49:44}, priority = {2}, title = {Connections between mRNA 3' end processing and transcription termination.}, url = {http://dx.doi.org/10.1016/j.ceb.2005.04.003}, volume = {17}, year = {2005} }

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TY - JOUR ID - citeulike:2928913 L3 - citeulike-article-id:2928913 TI - Connections between mRNA 3' end processing and transcription termination. JF - Current opinion in cell biology VL - 17 IS - 3 SP - 257 EP - 261 AD - Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA. SteveB@hms.harvard.edu SN - 0955-0674 N2 - Discoveries within the last few years have revealed that the multiple steps in gene expression are remarkably integrated. There have recently been several advances in deciphering how mRNA 3' end processing is linked with transcription elongation and termination. It has been known for quite a long time that transcription termination is somehow intertwined with polyadenylation, but it is still unclear exactly how these two processes influence each other. Some recent reports are shedding light on these connections. KW - polyadenylation KW - review KW - termination KW - transcription AU - Buratowski, S PY - 2005/06// UR - http://dx.doi.org/10.1016/j.ceb.2005.04.003 ER -

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