Neural Systems Responding to Degrees of Uncertainty in Human Decision-Making

by: Ming Hsu, Meghana Bhatt, Ralph Adolphs, Daniel Tranel, Colin F Camerer

Science, Vol. 310, No. 5754. (9 December 2005), pp. 1680-1683.

View FullText article

DOI, HighWire, Pubmed, Hubmed

Reviews [Write a review of this article]

There are no reviews of this article

Find related articles from these CiteULike users

brian, oamg, stefanherzog, ullrichbartsch, PaulBHartzog, suizan, Glimcher_Lab (group), ACS-Basel (group), zhenbo_cheng, bach, shupsy

Find related articles with these CiteULike tags

ambiguity, amygdala, decisionmaking, decision_making, decision-making, decsion_making, fmri, human, human_processing, neural, neurobiology, neuroeconomics, neuropsychology, neuroscience, reward, risk, uncertainty

Referat

Much is known about how people make decisions under varying levels of probability (risk). Less is known about the neural basis of decision-making when probabilities are uncertain because of missing information (ambiguity). In decision theory, ambiguity about probabilities should not affect choices. Using functional brain imaging, we show that the level of ambiguity in choices correlates positively with activation in the amygdala and orbitofrontal cortex, and negatively with a striatal system. Moreover, striatal activity correlates positively with expected reward. Neurological subjects with orbitofrontal lesions were insensitive to the level of ambiguity and risk in behavioral choices. These data suggest a general neural circuit responding to degrees of uncertainty, contrary to decision theory.

@article{citeulike:465989, abstract = {Much is known about how people make decisions under varying levels of probability (risk). Less is known about the neural basis of decision-making when probabilities are uncertain because of missing information (ambiguity). In decision theory, ambiguity about probabilities should not affect choices. Using functional brain imaging, we show that the level of ambiguity in choices correlates positively with activation in the amygdala and orbitofrontal cortex, and negatively with a striatal system. Moreover, striatal activity correlates positively with expected reward. Neurological subjects with orbitofrontal lesions were insensitive to the level of ambiguity and risk in behavioral choices. These data suggest a general neural circuit responding to degrees of uncertainty, contrary to decision theory.}, author = {Hsu, Ming and Bhatt, Meghana and Adolphs, Ralph and Tranel, Daniel and Camerer, Colin F. }, citeulike-article-id = {465989}, doi = {10.1126/science.1115327}, journal = {Science}, keywords = {ambiguity, amygdala, decision-making, decsion\_making, human\_processing, neuroeconomics, neuroscience, risk, uncertainty}, month = {December}, number = {5754}, pages = {1680--1683}, posted-at = {2007-07-16 18:18:42}, priority = {2}, title = {Neural Systems Responding to Degrees of Uncertainty in Human Decision-Making}, url = {http://dx.doi.org/10.1126/science.1115327}, volume = {310}, year = {2005} }

RIS record

TY - JOUR ID - citeulike:465989 L3 - citeulike-article-id:465989 TI - Neural Systems Responding to Degrees of Uncertainty in Human Decision-Making JF - Science VL - 310 IS - 5754 SP - 1680 EP - 1683 N2 - Much is known about how people make decisions under varying levels of probability (risk). Less is known about the neural basis of decision-making when probabilities are uncertain because of missing information (ambiguity). In decision theory, ambiguity about probabilities should not affect choices. Using functional brain imaging, we show that the level of ambiguity in choices correlates positively with activation in the amygdala and orbitofrontal cortex, and negatively with a striatal system. Moreover, striatal activity correlates positively with expected reward. Neurological subjects with orbitofrontal lesions were insensitive to the level of ambiguity and risk in behavioral choices. These data suggest a general neural circuit responding to degrees of uncertainty, contrary to decision theory. KW - ambiguity KW - amygdala KW - decision-making KW - decsion_making KW - human_processing KW - neuroeconomics KW - neuroscience KW - risk KW - uncertainty AU - Hsu, Ming AU - Bhatt, Meghana AU - Adolphs, Ralph AU - Tranel, Daniel AU - Camerer, Colin PY - 2005/12/09/ UR - http://dx.doi.org/10.1126/science.1115327 ER -

RIS BibTeX