Intensity versus identity coding in an olfactory system.

@article{citeulike:312788, abstract = {We examined the encoding and decoding of odor identity and intensity by neurons in the antennal lobe and the mushroom body, first and second relays, respectively, of the locust olfactory system. Increased odor concentration led to changes in the firing patterns of individual antennal lobe projection neurons (PNs), similar to those caused by changes in odor identity, thus potentially confounding representations for identity and concentration. However, when these time-varying responses were examined across many PNs, concentration-specific patterns clustered by identity, resolving the apparent confound. This is because PN ensemble representations changed relatively continuously over a range of concentrations of each odorant. The PNs' targets in the mushroom body-Kenyon cells (KCs)-had sparse identity-specific responses with diverse degrees of concentration invariance. The tuning of KCs to identity and concentration and the patterning of their responses are consistent with piecewise decoding of their PN inputs over oscillation-cycle length epochs.}, address = {California Institute of Technology, Division of Biology, Computation and Neural Systems Program, Pasadena, CA 91125, USA.}, author = {Stopfer, M. and Jayaraman, V. and Laurent, G. }, citeulike-article-id = {312788}, issn = {0896-6273}, journal = {Neuron}, keywords = {encoding, insects, olfactory}, month = {September}, number = {6}, pages = {991--1004}, posted-at = {2007-12-07 12:03:35}, priority = {2}, title = {Intensity versus identity coding in an olfactory system.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/12971898}, volume = {39}, year = {2003} }

TY - JOUR ID - citeulike:312788 L3 - citeulike-article-id:312788 TI - Intensity versus identity coding in an olfactory system. JF - Neuron VL - 39 IS - 6 SP - 991 EP - 1004 AD - California Institute of Technology, Division of Biology, Computation and Neural Systems Program, Pasadena, CA 91125, USA. SN - 0896-6273 N2 - We examined the encoding and decoding of odor identity and intensity by neurons in the antennal lobe and the mushroom body, first and second relays, respectively, of the locust olfactory system. Increased odor concentration led to changes in the firing patterns of individual antennal lobe projection neurons (PNs), similar to those caused by changes in odor identity, thus potentially confounding representations for identity and concentration. However, when these time-varying responses were examined across many PNs, concentration-specific patterns clustered by identity, resolving the apparent confound. This is because PN ensemble representations changed relatively continuously over a range of concentrations of each odorant. The PNs' targets in the mushroom body-Kenyon cells (KCs)-had sparse identity-specific responses with diverse degrees of concentration invariance. The tuning of KCs to identity and concentration and the patterning of their responses are consistent with piecewise decoding of their PN inputs over oscillation-cycle length epochs. KW - encoding KW - insects KW - olfactory AU - Stopfer, M AU - Jayaraman, V AU - Laurent, G PY - 2003/09/11/ UR - http://view.ncbi.nlm.nih.gov/pubmed/12971898 ER -