Functional Specialization of the Primate Frontal Cortex during Decision Making

@article{citeulike:1532683, abstract = {Economic theories of decision making are based on the principle of utility maximization, and reinforcement-learning theory provides computational algorithms that can be used to estimate the overall reward expected from alternative choices. These formal models not only account for a large range of behavioral observations in human and animal decision makers, but also provide useful tools for investigating the neural basis of decision making. Nevertheless, in reality, decision makers must combine different types of information about the costs and benefits associated with each available option, such as the quality and quantity of expected reward and required work. In this article, we put forward the hypothesis that different subdivisions of the primate frontal cortex may be specialized to focus on different aspects of dynamic decision-making processes. In this hypothesis, the lateral prefrontal cortex is primarily involved in maintaining the state representation necessary to identify optimal actions in a given environment. In contrast, the orbitofrontal cortex and the anterior cingulate cortex might be primarily involved in encoding and updating the utilities associated with different sensory stimuli and alternative actions, respectively. These cortical areas are also likely to contribute to decision making in a social context. 10.1523/JNEUROSCI.1561-07.2007}, author = {Lee, Daeyeol and Rushworth, Matthew F. and Walton, Mark E. and Watanabe, Masataka and Sakagami, Masamichi }, citeulike-article-id = {1532683}, doi = {http://dx.doi.org/10.1523/JNEUROSCI.1561-07.2007}, journal = {J. Neurosci.}, keywords = {cingulate, decision, model, monkeys, ofc, pfc, review}, month = {August}, number = {31}, pages = {8170--8173}, posted-at = {2007-08-03 10:17:54}, priority = {2}, title = {Functional Specialization of the Primate Frontal Cortex during Decision Making}, url = {http://dx.doi.org/10.1523/JNEUROSCI.1561-07.2007}, volume = {27}, year = {2007} }

TY - JOUR ID - citeulike:1532683 L3 - citeulike-article-id:1532683 TI - Functional Specialization of the Primate Frontal Cortex during Decision Making JF - J. Neurosci. VL - 27 IS - 31 SP - 8170 EP - 8173 N2 - Economic theories of decision making are based on the principle of utility maximization, and reinforcement-learning theory provides computational algorithms that can be used to estimate the overall reward expected from alternative choices. These formal models not only account for a large range of behavioral observations in human and animal decision makers, but also provide useful tools for investigating the neural basis of decision making. Nevertheless, in reality, decision makers must combine different types of information about the costs and benefits associated with each available option, such as the quality and quantity of expected reward and required work. In this article, we put forward the hypothesis that different subdivisions of the primate frontal cortex may be specialized to focus on different aspects of dynamic decision-making processes. In this hypothesis, the lateral prefrontal cortex is primarily involved in maintaining the state representation necessary to identify optimal actions in a given environment. In contrast, the orbitofrontal cortex and the anterior cingulate cortex might be primarily involved in encoding and updating the utilities associated with different sensory stimuli and alternative actions, respectively. These cortical areas are also likely to contribute to decision making in a social context. 10.1523/JNEUROSCI.1561-07.2007 KW - cingulate KW - decision KW - model KW - monkeys KW - ofc KW - pfc KW - review AU - Lee, Daeyeol AU - Rushworth, Matthew AU - Walton, Mark AU - Watanabe, Masataka AU - Sakagami, Masamichi PY - 2007/08/01/ UR - http://dx.doi.org/10.1523/JNEUROSCI.1561-07.2007 ER -