Medial prefrontal cell activity signaling prediction errors of action values

@article{citeulike:1248740, author = {Matsumoto, Madoka and Matsumoto, Kenji and Abe, Hiroshi and Tanaka, Keiji }, citeulike-article-id = {1248740}, comment = {To adapt behavior to a changing environment, one must monitor outcomes of executed actions and adjust subsequent actions accordingly. Involvement of the medial frontal cortex in performance monitoring has been suggested, but little is known about neural processes that link performance monitoring to performance adjustment. Here, we recorded from neurons in the medial prefrontal cortex of monkeys learning arbitrary action-outcome contingencies. Some cells preferentially responded to positive visual feedback stimuli and others to negative feedback stimuli. The magnitude of responses to positive feedback stimuli decreased over the course of behavioral adaptation, in correlation with decreases in the amount of prediction error of action values. Therefore, these responses in medial prefrontal cells may signal the direction and amount of error in prediction of values of executed actions to specify the adjustment in subsequent action selections.}, doi = {http://dx.doi.org/10.1038/nn1890}, issn = {1097-6256}, journal = {Nature Neuroscience}, keywords = {action-selection, monkeys, pfc, value}, month = {April}, number = {5}, pages = {647--656}, posted-at = {2007-05-22 10:18:04}, priority = {4}, publisher = {Nature Publishing Group}, title = {Medial prefrontal cell activity signaling prediction errors of action values}, url = {http://dx.doi.org/10.1038/nn1890}, volume = {10}, year = {2007} }

TY - JOUR ID - citeulike:1248740 L3 - citeulike-article-id:1248740 TI - Medial prefrontal cell activity signaling prediction errors of action values JF - Nature Neuroscience VL - 10 IS - 5 SP - 647 EP - 656 PB - Nature Publishing Group SN - 1097-6256 KW - action-selection KW - monkeys KW - pfc KW - value N1 - To adapt behavior to a changing environment, one must monitor outcomes of executed actions and adjust subsequent actions accordingly. Involvement of the medial frontal cortex in performance monitoring has been suggested, but little is known about neural processes that link performance monitoring to performance adjustment. Here, we recorded from neurons in the medial prefrontal cortex of monkeys learning arbitrary action-outcome contingencies. Some cells preferentially responded to positive visual feedback stimuli and others to negative feedback stimuli. The magnitude of responses to positive feedback stimuli decreased over the course of behavioral adaptation, in correlation with decreases in the amount of prediction error of action values. Therefore, these responses in medial prefrontal cells may signal the direction and amount of error in prediction of values of executed actions to specify the adjustment in subsequent action selections. AU - Matsumoto, Madoka AU - Matsumoto, Kenji AU - Abe, Hiroshi AU - Tanaka, Keiji PY - 2007/04/22/ UR - http://dx.doi.org/10.1038/nn1890 ER -