Forces of Interaction between DNA-Grafted Colloids: An Optical Tweezer Measurement

by: K Kegler, M Salomo, F Kremer

Physical Review Letters, Vol. 98, No. 5. (2007)

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Optical tweezers are employed to measure the forces of interaction between single DNA-grafted colloids. Parameters to be varied are the length of the DNA, the grafting density, and the ion concentration of the surrounding medium. From the measured force-separation dependence an interaction length at a given force is deduced. It shows in the mushroom regime a scaling with the grafting density which levels off for brushes. For the latter the transition from an osmotic to a salted brush can be traced in detail by varying the ion concentration in accordance with mean field theories.

@article{citeulike:2563086, abstract = {Optical tweezers are employed to measure the forces of interaction between single DNA-grafted colloids. Parameters to be varied are the length of the DNA, the grafting density, and the ion concentration of the surrounding medium. From the measured force-separation dependence an interaction length at a given force is deduced. It shows in the mushroom regime a scaling with the grafting density which levels off for brushes. For the latter the transition from an osmotic to a salted brush can be traced in detail by varying the ion concentration in accordance with mean field theories.}, author = {Kegler, K. and Salomo, M. and Kremer, F. }, citeulike-article-id = {2563086}, doi = {10.1103/PhysRevLett.98.058304}, journal = {Physical Review Letters}, keywords = {2007, biology, colloids, opticaltweezer}, number = {5}, posted-at = {2008-03-19 17:00:52}, priority = {2}, publisher = {APS}, title = {Forces of Interaction between DNA-Grafted Colloids: An Optical Tweezer Measurement}, url = {http://scitation.aip.org/getabs/servlet/GetabsServlet?prog=normal\&id=PRLTAO000098000005058304000001\&idtype=cvips\&gifs=yes}, volume = {98}, year = {2007} }

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TY - JOUR ID - citeulike:2563086 L3 - citeulike-article-id:2563086 TI - Forces of Interaction between DNA-Grafted Colloids: An Optical Tweezer Measurement JF - Physical Review Letters VL - 98 IS - 5 PB - APS N2 - Optical tweezers are employed to measure the forces of interaction between single DNA-grafted colloids. Parameters to be varied are the length of the DNA, the grafting density, and the ion concentration of the surrounding medium. From the measured force-separation dependence an interaction length at a given force is deduced. It shows in the mushroom regime a scaling with the grafting density which levels off for brushes. For the latter the transition from an osmotic to a salted brush can be traced in detail by varying the ion concentration in accordance with mean field theories. KW - 2007 KW - biology KW - colloids KW - opticaltweezer AU - Kegler, K AU - Salomo, M AU - Kremer, F PY - 2007/// UR - http://scitation.aip.org/getabs/servlet/GetabsServlet?prog=normal&id=PRLTAO000098000005058304000001&idtype=cvips&gifs=yes ER -

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