Isolation and mapping of human homologues of an imprinted mouse gene U2af1-rs1.

@article{citeulike:2343209, abstract = {We have isolated human homologues of the imprinted mouse gene, U2af1-rs1. Two different types of cDNAs and three distinct genomic DNAs belonging to different groups were isolated. We have identified chromosomal genes corresponding to each cDNA by restriction mapping and sequencing. Using both a panel of rodent/human somatic cell hybrids and fluorescence in situ hybridization, group 1 and group 2 genes were mapped to chromosome 5q22 and chromosome Xp22.1, respectively. We designated group 1 and group 2 genes as human U2AF1-RS1 and U2AF1-RS2, respectively, because these genes corresponded to mouse U2af1-rs1 (chromosome 11) and U2af1-rs2 (chromosome X), which we also isolated and mapped. Amino acid sequences of human U2AF1-RS1 and U2AF-RS2 showed significant homology to U2AF small subunit. The group 3 gene, designated as U2AF1-RS3, of which the cDNA has not yet been isolated, was mapped to chromosome 19p13.2.}, address = {Department of Bioscience, National Cardiovascular Center Research Institute, Osaka, Japan.}, author = {Kitagawa, K. and Wang, X. and Hatada, I. and Yamaoka, T. and Nojima, H. and Inazawa, J. and Abe, T. and Mitsuya, K. and Oshimura, M. and Murata, A. }, citeulike-article-id = {2343209}, issn = {0888-7543}, journal = {Genomics}, keywords = {human, u2af1-rs1}, month = {November}, number = {2}, pages = {257--263}, posted-at = {2008-02-06 19:49:48}, priority = {2}, title = {Isolation and mapping of human homologues of an imprinted mouse gene U2af1-rs1.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/8586425}, volume = {30}, year = {1995} }

TY - JOUR ID - citeulike:2343209 L3 - citeulike-article-id:2343209 TI - Isolation and mapping of human homologues of an imprinted mouse gene U2af1-rs1. JF - Genomics VL - 30 IS - 2 SP - 257 EP - 263 AD - Department of Bioscience, National Cardiovascular Center Research Institute, Osaka, Japan. SN - 0888-7543 N2 - We have isolated human homologues of the imprinted mouse gene, U2af1-rs1. Two different types of cDNAs and three distinct genomic DNAs belonging to different groups were isolated. We have identified chromosomal genes corresponding to each cDNA by restriction mapping and sequencing. Using both a panel of rodent/human somatic cell hybrids and fluorescence in situ hybridization, group 1 and group 2 genes were mapped to chromosome 5q22 and chromosome Xp22.1, respectively. We designated group 1 and group 2 genes as human U2AF1-RS1 and U2AF1-RS2, respectively, because these genes corresponded to mouse U2af1-rs1 (chromosome 11) and U2af1-rs2 (chromosome X), which we also isolated and mapped. Amino acid sequences of human U2AF1-RS1 and U2AF-RS2 showed significant homology to U2AF small subunit. The group 3 gene, designated as U2AF1-RS3, of which the cDNA has not yet been isolated, was mapped to chromosome 19p13.2. KW - human KW - u2af1-rs1 AU - Kitagawa, K AU - Wang, X AU - Hatada, I AU - Yamaoka, T AU - Nojima, H AU - Inazawa, J AU - Abe, T AU - Mitsuya, K AU - Oshimura, M AU - Murata, A PY - 1995/11/20/ UR - http://view.ncbi.nlm.nih.gov/pubmed/8586425 ER -